Notes
Mechanism of Wolff-Kishner Reduction…
Mechanism of Wolff-Kishner Reduction:
(i) The hydrazone formation involves the nucleophilic addition of the hydrazine to the carbonyl carbon, followed by elimination of water. The resulting hydrazone is a stable compound.
(ii) The hydrazone is then treated with a strong base, forming a carbanion intermediate.
(iii) The process involves migration of the alkyl group from the nitrogen atom to the carbon adjacent to the carbonyl carbon, breaking the carbon-nitrogen bond in the process.
Subscribe to our youtube channel!
Staying up to date on Question/Notes related to General knowledge, current affairs and are useful in Academic and Government Exams. More than 8000 video on our channel.
Subscribe